Macular degeneration trial will be first human test of Nobel-winning stem cell technique

18 January 2019
Source: STAT

Curing diabetes with stem cells? Everyone knew that would be hard. Parkinson’s disease? Harder. Alzheimer’s? Probably impossible. But age-related macular degeneration, a major cause of blindness? That was supposed to be low-hanging fruit. The cause of AMD is well-known, the recipe for turning stem cells into retinal cells works like a charm, and the eye is “immunoprivileged,” meaning immune cells

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BBC News: Brexit: Universities warn no deal is ‘biggest-ever threat’

4 January 2019
Source: BBC News

University heads are warning a no-deal Brexit is “one of the biggest threats” the institutions have ever faced. Higher education leaders have written to MPs to say it is “no exaggeration” to warn that it would take universities “decades to recover”. They say it would undermine scientific research and threaten universities’ £21bn contribution to the UK economy. See the full

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Therapeutic Advances in Ophthalmology: Corneal endothelial cell dysfunction: etiologies and management

7 December 2018
Source: Therapeutic Advances in Ophthalmology

Abstract   A transparent cornea is essential for the formation of a clear image on the retina. The human cornea is arranged into well-organized layers, and each layer plays a significant role in maintaining the transparency and viability of the tissue. The endothelium has both barrier and pump functions, which are important for the maintenance of corneal clarity. Many etiologies,

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Retina UK: Gene therapy for RPE65 gene approved for use in EU

23 November 2018
Source: Retina UK

The gene therapy Luxturna has won European regulatory approval for the treatment of Inherited retinal dystrophy caused by mutations in the RPE65 gene. This milestone decision was made by the European Medicines Agency (EMA) on Thursday, 22 November. Luxturna is the first and only gene therapy available in Europe to treat inherited retinal disease. It had already been approved for

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NIHR: Eye disease patients have more opportunity than ever to take part in NHS research studies

21 November 2018
Source: NIHR

• 76 per cent of hospitals in England now offer patients the opportunity to take part in eye disease studies • 15,500 patients per year offered innovative treatments for diseases such as age-related macular degeneration • Ophthalmology community ‘punching above its weight’ in world of research A new paper published today highlights how some 76 per cent of hospitals in

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Macular Society: Diabetes medication may protect against AMD

14 November 2018
Source: Macular Society

Researchers from Taiwan have shown that people with type 2 diabetes who took a common diabetes medication, had a significantly lower rate of age-related macular degeneration (AMD). The study suggests that the anti-inflammatory and anti-oxidative effects of the drug metformin can protect against AMD, while it controls diabetes. The research was presented at AAO 2018, the 122nd Annual Meeting of

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University of Nottingham: Eye discovery to pave way for more successful corneal transplants

6 October 2018

A team of eye specialists at the University of Nottingham has made another novel discovery  that could help to improve the success of corneal transplants for patients whose sight has been affected by disease. The research, published in the October edition of the American Journal of Ophthalmology, has shed light on a characteristic of a thin membrane called the Descemets

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National Eye Health Week 2018: Research funding will use iPads to identify the best method to manage nystagmus

28 September 2018
Source: Fight for Sight and Nystagmus Network

Fight for Sight and The Nystagmus Network have announced funding for three exciting nystagmus research projects at the Nystagmus Network Conference, which is taking place today during National Eye Health Week 2018. In total £30,000 in funding will be used for projects bringing benefits to children and adults living with the condition, which is characterised by involuntary and repetitive movements

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Macular Society, National Eye Health Week – Could our immune system be causing AMD?

28 September 2018
Source: Macular Society

Imagine not being able to read the newspaper, or enjoy the autumn flowers in the garden? Imagine seeing fuzzy images and blurred lines? This is what people living with Macular Degeneration, or AMD, deal with every day. In the UK, around 600,000 people are living with AMD and around 70,000 new cases are diagnosed every year: that’s nearly 200 every

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